This is a short summary of a topological model of site-specific recombination, a cellular reaction that creates knots and links out of circular double stranded DNA molecules. The model is used to predict and characterise the topology of the products of a reaction on double stranded DNA twist knots. It is shown that all such products fall into a small family of Montesinos knots and links, meaning that the knot and link type of possible products is significantly reduced, thus aiding their experimental identification. We also mention direct applications of the model.
@article{bwmeta1.element.bwnjournal-article-doi-10_4064-bc100-0-13,
author = {Karin Valencia},
title = {A topological model of site-specific recombination that predicts the knot and link type of DNA products},
journal = {Banach Center Publications},
volume = {102},
year = {2014},
pages = {223-233},
zbl = {1287.57014},
language = {en},
url = {http://dml.mathdoc.fr/item/bwmeta1.element.bwnjournal-article-doi-10_4064-bc100-0-13}
}
Karin Valencia. A topological model of site-specific recombination that predicts the knot and link type of DNA products. Banach Center Publications, Tome 102 (2014) pp. 223-233. http://gdmltest.u-ga.fr/item/bwmeta1.element.bwnjournal-article-doi-10_4064-bc100-0-13/