Plusieurs travaux de pharmacologie du comportement, effectués chez les rongeurs, montrent que des mécanismes communs existent dans l'épilepsie, dans certaines formes d'anxiété et dans certains processus mnésiques. La raison en est sans doute l'ubiquité d'un médiateur cérébral appelé le GABA et qui intervient à la fois dans les trois phénomènes. L'analyse de ces résultats permet de suggérer que le fonctionnement normal du cerveau repose sur une anxiété légère. Les conséquences épistémologiques et philosophiques en sont discutées.
A number of studies on the pharmacology of behaviour conducted on rodents have revealed that mechanisms involved in epilepsy were also found in certain forms of anxiety and certain mnesic processes. This is probably due to the widespread presence of a cerebral transmitter named GABA which plays a role in all three phenomena. An analysis of the findings suggests the hypothesis that normal brain function is based on mild anxiety. The discussion deals with the epistemological and philosophical ramifications.
@article{PHSC_2002__6_1_75_0,
author = {Chapouthier, Georges and Lepicard, Eve M. and R\"ossler, Anne Sophie and Venault, Patrice},
title = {L'anxi\'et\'e, un pont entre l'\'epilepsie et la m\'emoire~?},
journal = {Philosophia Scientiae},
volume = {6},
year = {2002},
pages = {75-91},
language = {fr},
url = {http://dml.mathdoc.fr/item/PHSC_2002__6_1_75_0}
}
Chapouthier, Georges; Lepicard, Eve M.; Rössler, Anne Sophie; Venault, Patrice. L'anxiété, un pont entre l'épilepsie et la mémoire ?. Philosophia Scientiae, Tome 6 (2002) pp. 75-91. http://gdmltest.u-ga.fr/item/PHSC_2002__6_1_75_0/
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