A Non-Markovian Model for Cell Population Growth: Tail Behavior and Duration of the Growth Process
de Gunst, Mathisca C. M. ; van Zwet, Willem R.
Ann. Appl. Probab., Tome 3 (1993) no. 4, p. 1112-1144 / Harvested from Project Euclid
De Gunst has formulated a stochastic model for the growth of a certain type of plant cell population that initially consists of $n$ cells. The total cell number $N_n(t)$ as predicted by the model is a non-Markovian counting process. The relative growth of the population, $n^{-1}(N_n(t) - n)$, converges almost surely uniformly to a nonrandom function $X$. In the present paper we investigate the behavior of the limit process $X(t)$ as $t$ tends to infinity and determine the order of magnitude of the duration of the process $N_n(t)$. There are two possible causes for the process $N_n$ to stop growing, and correspondingly, the limit process $X(t)$ has a derivative $X'(t)$ that is the product of two factors, one or both of which may tend to zero as $t$ tends to infinity. It turns out that there is a remarkable discontinuity in the tail behavior of the processes. We find that if only one factor of $X'(t)$ tends to zero, then the rate at which the limit process reaches its final limit is much faster and the order of magnitude of the duration of the process $N_n$ is much smaller than when both occur approximately at the same time.
Publié le : 1993-11-14
Classification:  Stochastic model,  population growth,  non-Markovian counting process,  tail behavior,  duration,  60G55,  60F99,  62P10
@article{1177005275,
     author = {de Gunst, Mathisca C. M. and van Zwet, Willem R.},
     title = {A Non-Markovian Model for Cell Population Growth: Tail Behavior and Duration of the Growth Process},
     journal = {Ann. Appl. Probab.},
     volume = {3},
     number = {4},
     year = {1993},
     pages = { 1112-1144},
     language = {en},
     url = {http://dml.mathdoc.fr/item/1177005275}
}
de Gunst, Mathisca C. M.; van Zwet, Willem R. A Non-Markovian Model for Cell Population Growth: Tail Behavior and Duration of the Growth Process. Ann. Appl. Probab., Tome 3 (1993) no. 4, pp.  1112-1144. http://gdmltest.u-ga.fr/item/1177005275/