The Infinitely-Many-Sites Model as a Measure-Valued Diffusion
Ethier, S. N. ; Griffiths, R. C.
Ann. Probab., Tome 15 (1987) no. 4, p. 515-545 / Harvested from Project Euclid
The infinitely-many-sites model (with no recombination) is reformulated, with sites labelled by elements of [0, 1] and "type" space $E = \lbrack 0, 1\rbrack^{\mathbb{Z}_+}$. A gene is of type $\mathbf{x} = (x_0, x_1,\ldots) \in E$ if $x_0, x_1, \ldots$ is the sequence of sites at which mutations have occurred in the line of descent of that gene. The model is approximated by a diffusion process taking values in $\mathscr{P}^0_a(E)$, the set of purely atomic Borel probability measures $\mu$ on $E$ with the property that the locations of every $n \geq 1$ atoms of $\mu$ form a family tree, and the diffusion is shown to have a unique stationary distribution $\tilde{\mu}$. The principal object of investigation is the $\tilde{\mu}(d\mu)$-expectation of the probability that a random sample from a population with types distributed according to $\mu$ has a given tree structure. Ewens' (1972) sampling formula and Watterson's (1975) segregating-sites distribution are obtained as corollaries.
Publié le : 1987-04-14
Classification:  Measure-valued diffusion,  population genetics,  infinitely-many-sites model,  infinitely-many-alleles model,  segregating sites,  family trees,  sampling distributions,  60G57,  60J70,  92A10
@article{1176992157,
     author = {Ethier, S. N. and Griffiths, R. C.},
     title = {The Infinitely-Many-Sites Model as a Measure-Valued Diffusion},
     journal = {Ann. Probab.},
     volume = {15},
     number = {4},
     year = {1987},
     pages = { 515-545},
     language = {en},
     url = {http://dml.mathdoc.fr/item/1176992157}
}
Ethier, S. N.; Griffiths, R. C. The Infinitely-Many-Sites Model as a Measure-Valued Diffusion. Ann. Probab., Tome 15 (1987) no. 4, pp.  515-545. http://gdmltest.u-ga.fr/item/1176992157/