Nonparametric Approaches to the Analysis of Crossover Studies
Putt, Mary E. ; Chinchilli, Vernon M.
Statist. Sci., Tome 19 (2004) no. 1, p. 712-719 / Harvested from Project Euclid
We illustrate nonparametric, and particularly rank-based analyses of crossover studies, designs in which each subject receives more than one treatment over time. Principles involved in using the Wilcoxon rank sum test in the simple two-period, two-treatment crossover are described through theory and example. We then extend the ideas to two-treatment designs with more than two periods and to three-treatment, three-period designs. When more than one nonparametric approach is available, we consider the issue of statistical power in choosing an appropriate test.
Publié le : 2004-11-14
Classification:  Crossover,  clinical trials,  nonparametrics,  rank-based statistics
@article{1113832735,
     author = {Putt, Mary E. and Chinchilli, Vernon M.},
     title = {Nonparametric Approaches to the Analysis of Crossover Studies},
     journal = {Statist. Sci.},
     volume = {19},
     number = {1},
     year = {2004},
     pages = { 712-719},
     language = {en},
     url = {http://dml.mathdoc.fr/item/1113832735}
}
Putt, Mary E.; Chinchilli, Vernon M. Nonparametric Approaches to the Analysis of Crossover Studies. Statist. Sci., Tome 19 (2004) no. 1, pp.  712-719. http://gdmltest.u-ga.fr/item/1113832735/