For response-adaptive clinical trials using a generalized Friedman's urn design, we derive the asymptotic normality of the sample fraction assigned to each treatment under staggered entry and delayed response. The rate of convergence and the law of the iterated logarithm are obtained for both the urn composition and the sample fraction. Some applications are also discussed.
@article{1089206406,
author = {Hu, Feifang and Zhang, Li-Xin},
title = {Asymptotic normality of urn models for clinical trials with delayed response},
journal = {Bernoulli},
volume = {10},
number = {2},
year = {2004},
pages = { 447-463},
language = {en},
url = {http://dml.mathdoc.fr/item/1089206406}
}
Hu, Feifang; Zhang, Li-Xin. Asymptotic normality of urn models for clinical trials with delayed response. Bernoulli, Tome 10 (2004) no. 2, pp. 447-463. http://gdmltest.u-ga.fr/item/1089206406/