The breathing pattern was studied in man during inspiratory elastic load applied throughout the breathing cycle (CL) or inspiration only (DL). decreased similarly under both loads — 40% during the 1st loaded breath (1st), 25% after 1 min (min) — as did Ti (15% at 1st, 25% at min); Te decreased by 35% under CL, 25% under DL, at both times. Under DL expiratory flow started after a lag of 0.4 sec, required to raise alveolar pressure above atmospheric pressure. In all subjects the inspiratory drive was increased at 1st and in 6 out of 8 the ventilatory response at min was essentially neurogenic. The rate of decrease of inspiratory muscle pressure during the period of zero flow under DL was proportional to end-inspiratory muscle pressure (Pmus{e.i.}) and to Pmus{e.i.}/Ti. At the beginning of expiration dPmus/dt was greater under DL: in this period the difference of Pmus between CL and DL seems mainly due to intrinsic muscle properties.
@article{RLINA_1977_8_63_5_454_0, author = {Emilio Agostoni and Edgardo D'Angelo and Marco Piolini}, title = {Modalit\`a del respiro nell'uomo sottoposto a carichi elastici inspiratori}, journal = {Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti}, volume = {62}, year = {1977}, pages = {454-457}, language = {it}, url = {http://dml.mathdoc.fr/item/RLINA_1977_8_63_5_454_0} }
Agostoni, Emilio; D'Angelo, Edgardo; Piolini, Marco. Modalità del respiro nell'uomo sottoposto a carichi elastici inspiratori. Atti della Accademia Nazionale dei Lincei. Classe di Scienze Fisiche, Matematiche e Naturali. Rendiconti, Tome 62 (1977) pp. 454-457. http://gdmltest.u-ga.fr/item/RLINA_1977_8_63_5_454_0/
The influence of the “chest wall” on respiratory rate and depth, «Respir. Physiol.», 3, 47-54.
, , e (1967) -The immediate effects of elastic loads on the breathing of man, «J. Physiol. (London)», 156, 260-273.
, e (1961) -Immediate ventilatory response to elastic loads and positive pressure in man, «Respir. Physiol.», 18, 347-369.
, , , , e (1973) -Role of the diaphragm in breathing in conscious normal man: an electromyographic study, «J. Appl. Physiol.», 15, 1101-1106.
, and (1960) -The effect of elastic and resistive loading of inspiration on the breathing of conscious man, «Respir. Physiol.», 4, 363-372.
, e (1968) -Posthyper-ventilation isocapnic hyperpnea, «J. Appl. Physiol.», 40, 592-596.
, e (1976) -