La statistica nelle prove cliniche
Gasparini, Mauro
Bollettino dell'Unione Matematica Italiana, Tome 6-A (2003), p. 119-140 / Harvested from Biblioteca Digitale Italiana di Matematica
Access to full text
Full (PDF)
Full (DjVu)

Si descrivono le attività e le responsabilità dello statistico professionale nella conduzione di una prova clinica in una industria farmaceutica o in un ente di ricerca.

Publié le : 2003-04-01
@article{BUMI_2003_8_6A_1_119_0,
     author = {Mauro Gasparini},
     title = {La statistica nelle prove cliniche},
     journal = {Bollettino dell'Unione Matematica Italiana},
     volume = {6-A},
     year = {2003},
     pages = {119-140},
     zbl = {1194.62113},
     mrnumber = {1982350},
     language = {it},
     url = {http://dml.mathdoc.fr/item/BUMI_2003_8_6A_1_119_0}
}

Gasparini, Mauro. La statistica nelle prove cliniche. Bollettino dell'Unione Matematica Italiana, Tome 6-A (2003) pp. 119-140. http://gdmltest.u-ga.fr/item/BUMI_2003_8_6A_1_119_0/

C. Buncher - J. Y. Tsay (Eds.), Statistics in the pharmaceutical industry, Dekker, second edition, 1994. | Zbl 1092.62116

Friedman, L. - Furberg, C. - Demets, D., Fundamentals of Clinical trials, Springer, third edition, 1998. | Zbl 1136.62072

Gibaldi, M. - Perrier, D., Pharmacokinetics, Dekker, 1982.

Goodman, S., Toward evidence-based medical statistics. 1: The P-value fallacy, Annals of Internal Medicine, 130(1999a), 995-1004.

Goodman, S., Toward evidence-based medical statistics. 2: The Bayes factor, Annals of Internal Medicine, 130(1999b), 1004-1013.

International Conferenceon Harmonization, Statistical principles for clinical trials, http://www.ifpma.org/ich5e.html (1998).

C. Jennison - B. Turnbull (Eds.), Group Sequential Methods with Applications to Clinical Trials, CRC Press, 1999. | MR 1710781 | Zbl 0934.62078

Millard, S. - Krause, A., Applied Statistics in the Pharmaceutical Industry, Springer, 2001. | Zbl 0979.62087

Piantadosi, S., Clinical Trials. A methodological perspective, Wiley, 1997. | MR 2154988 | Zbl 1081.62102

Racine-Poon, A. - Wakefield, J., Statistica methods for population pharmacokinetic modelling, Statistica Methods in Medical Research, 7 (1998), 63-84.

Senn, S., Statistical Issued in Drug Development, Wiley, 1997. | Zbl 1165.62086

Spiegelhalter, D. - Freedman, L. - Parmar, M., Bayesian approaches to randomized trials, Journal of the Royal Statistical Society series A, 157(1994), 357-416. | MR 1321308 | Zbl 1001.62529