One of the aims of the meta-analysis of clinical trials is to determine the efficacy of a new type oftreatment. This efficacy is commonly measured by the difference between the efficacy of a standardtreatment and the new treatment. For binary data the difference can be measured by a probabilitydifference. We investigate, by simulations and using box plots, the basic statistical properties of thepoint estimator of the probability difference of overall treatment effects in the meta-analysis based onmulticentre trials for various chosen situations. This estimator was suggested in Dokoupilova (2011).
@article{134, title = {A point estimator of the probability difference of overall treatment effect - simulation study}, journal = {Tatra Mountains Mathematical Publications}, volume = {49}, year = {2011}, doi = {10.2478/tatra.v50i3.134}, language = {EN}, url = {http://dml.mathdoc.fr/item/134} }
Krajíčková, Pavla. A point estimator of the probability difference of overall treatment effect - simulation study. Tatra Mountains Mathematical Publications, Tome 49 (2011) . doi : 10.2478/tatra.v50i3.134. http://gdmltest.u-ga.fr/item/134/