Global Dynamics of B Cells and Anti-Idiotipic B Cells and its Application to Autoimmunity
Sasaki, Toru ; Kajiwara, Tsuyoshi
Japan J. Indust. Appl. Math., Tome 24 (2007) no. 1, p. 105-118 / Harvested from Project Euclid
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Global behavior of B models is discussed. When the source term for new B cells equals zero, the system has a conservation quantity. It implies the structurally unstability. It suggests that lack of the source of new B cells may unstabilize the immune system. When the B model incorporates autoimmunity, it loses symmetry. The asymmetry suggests the transition from a tolerant state to autoimmune state is more likely than the inverse transition. Effect of dose of antigen is also considered.
Publié le : 2007-02-14
Classification:  B model,  global dynamics,  conservation quantity,  autoimmunity 
@article{1197390056,
     author = {Sasaki, Toru and Kajiwara, Tsuyoshi},
     title = {Global Dynamics of B Cells and Anti-Idiotipic B Cells and its
Application to Autoimmunity},
     journal = {Japan J. Indust. Appl. Math.},
     volume = {24},
     number = {1},
     year = {2007},
     pages = { 105-118},
     language = {en},
     url = {http://dml.mathdoc.fr/item/1197390056}
}

Sasaki, Toru; Kajiwara, Tsuyoshi. Global Dynamics of B Cells and Anti-Idiotipic B Cells and its
Application to Autoimmunity. Japan J. Indust. Appl. Math., Tome 24 (2007) no. 1, pp.  105-118. http://gdmltest.u-ga.fr/item/1197390056/