A Sequential Clinical Trial for Comparing Three Treatments
Siegmund, D.
Ann. Statist., Tome 21 (1993) no. 1, p. 464-483 / Harvested from Project Euclid
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A model for sequential clinical trials involving three treatments is proposed and various error probabilities are defined. A specific procedure involving a concatenation of repeated significance tests is studied in detail. The first phase of testing proceeds until at least one treatment is eliminated; and then a second phase is used to compare the remaining treatments. Analytic approximations to the operating characteristics of the test are derived and compared with the results of a Monte Carlo experiment.
Publié le : 1993-03-14
Classification:  Sequential test,  boundary crossing probability,  repeated significance test,  62L10,  62N10 
@article{1176349037,
     author = {Siegmund, D.},
     title = {A Sequential Clinical Trial for Comparing Three Treatments},
     journal = {Ann. Statist.},
     volume = {21},
     number = {1},
     year = {1993},
     pages = { 464-483},
     language = {en},
     url = {http://dml.mathdoc.fr/item/1176349037}
}

Siegmund, D. A Sequential Clinical Trial for Comparing Three Treatments. Ann. Statist., Tome 21 (1993) no. 1, pp.  464-483. http://gdmltest.u-ga.fr/item/1176349037/